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Reconstructing evolutionary history

Can I infer the past from present day observations?

Genes are passed on vertically from ancestor to offspring

A gene is not invented twice

Analysis

In this exercise, we will extract the sequences of a subset of orthologs for two PCD gene families from our interactive webtool. We will align these sequences and calculate a phylogenetic tree. This tree will then help us to better understand the evolutionary history of the gene family

Task 1: GH27_QRW17738.1

  1. Using the “Export data” option from the top menu, download all data as FASTA sequences
  2. Extract the sequences of GH27_QRW17738.1 orthologs for the following taxa:
    GH27_QRW17738.1_taxa.txt
    Rhizoctonia solani
Aspergillus oryzae
Trichomonas vaginalis
Cordyceps militaris
Bradysia coprophila
Hydra vulgaris
Notolabrus celidotus
Homo sapiens
  3. Align the sequences using ClustalOmega

Task 2: GH28_QRW23661.1

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