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Finding "corresponding" genes

How to identify “corresponding” genes across species


Genes in two species that originated from the same ancestral gene in the last common ancestor of the species are good candidates for being 'corresponding' genes (orthologs)

Orthologs are genes in two species that are mutually most similar to each other

Analysis

In this course, we will follow the steps of a comparative genomics analysis of plant cell wall degrading enzymes (PCDs). Plant cell walls are made up of cellulose and hemi-cellulose, making them two of the most common organic molecules on Earth and key components of the carbon cycle.

It was thought for a long time that PCDs are only produced by fungi and certain bacteria, but in recent years, evidence has accumulated that some invertebrate animals may be able to degrade plant cell walls as well.

Task 1: Exploration