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--- compgenomics:modul4 [2025/05/16 11:06] – felix
+++ compgenomics:modul4 [2025/05/16 11:12] (current) – [From gene presence to function] felix
@@ Line 8: / Line 8: @@
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-Information about gene activity can be extracted from the sequence
+**Assumption:** Information about gene activity can be extracted from the sequence
 </WRAP>
 ==== Analysis ====
+The functional analysis of a protein sequence typically involves the annotation of features that are directly or indirectly related to the activity of the protein. Examples include structural protein domains, regions of conserved sequence, signal peptides and transmembrane domains, and low-complexity regions. Alterations in protein feature architectures have been associated with changes in protein activity. Therefore, the comparison of features can help to find out whether orthologs have adapted a different molecular activity in the course of their evolution.
 === Task 1: The CE8 pectinase ===