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compgenomics:modul3 [2025/05/16 09:34] – felixcompgenomics:modul3 [2025/05/17 13:46] (current) – ingo
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 <WRAP round tip 500px center> <WRAP round tip 500px center>
-Genes are passed on vertically from ancestor to offspring+**Assumption 1:** Genes are passed on vertically from ancestor to offspring
 </WRAP> </WRAP>
  
 <WRAP round tip 500px center> <WRAP round tip 500px center>
-A gene is not invented twice+**Assumption 2:** A gene is not invented twice
 </WRAP> </WRAP>
  
Line 23: Line 23:
 === Task 1: GH27_QRW17738.1 === === Task 1: GH27_QRW17738.1 ===
  
-  - Using the "Export data" option from the top menu, download all data as <wrap tip>FASTA sequences</wrap> 
   - Extract the sequences of GH27_QRW17738.1 orthologs for the following taxa:<WRAP>   - Extract the sequences of GH27_QRW17738.1 orthologs for the following taxa:<WRAP>
 <file txt GH27_QRW17738.1_taxa.txt> <file txt GH27_QRW17738.1_taxa.txt>
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 Homo sapiens Homo sapiens
 </file></WRAP> </file></WRAP>
 +  - <wrap tip>To get the sequences</wrap> click on the dot in the columns of the respective species in the GH27_QRW17738.1 row (use the search boxes on the left to find them!). 
 +    * In the bottom left corner, you can click on "Detailed plot", opening up a window with more information that also contains the sequence. 
 +    * If no sequence is shown, look at the barcharts on the top of the page. Click on the highest barchart to select one gene from the available options. This will give you the sequence
 +    * Save the sequences in a [[https://de.wikipedia.org/wiki/FASTA-Format|FASTA file]] (use the species name in the FASTA header!)
   - Align the sequences using [[https://www.ebi.ac.uk/jdispatcher/msa/clustalo|ClustalOmega]]   - Align the sequences using [[https://www.ebi.ac.uk/jdispatcher/msa/clustalo|ClustalOmega]]
-  - +  - Inspect the distance tree generated by ClustalOmega. What can you learn? 
 + 
 +<hidden GH27_QRW17738.fa> 
 +<file txt GH27_QRW17738.fa> 
 +>GH27_QRW17738.1|RHISO@456999@016906535_1|XP_043177975.1|1 
 +MIGIPVATFIFLGCAIGIVDAQQPLYTQCGGMVGRSPHHYECCASAIGCWTQSPVGKTPALGWNSWNAYQGNINEAKIRAAADALVSLGLKDAGYNYVNIDDCWSNITGRDVGTSRIKPDLNKFPNGIKSVADYIHSLGLLVGIYSDAGTLTCAGFPGSLGYENIDAQTFAEWGIDYLKYDNCNVPSNWTDTYGGPDFDWYNSNSGIRYRQMTSALASVASIRPIQYGICNWGNADVWTWGSRVGHSWRMSGDSSASWSYITSIIARNTNYLNYVEFYGHNDMDMMEIGNGALTINEQRTHFAMWVALKSPILLGTDLSKLNATQLAIIKNAELLAFSQDTTVGAPAKPYKSGTTTPPEYYTGKSAKGTHVFIMNVGSAPASKIVTFSEVTGLTCTSCKVHDMWTGKGKCIFSHTTTIVFNCGLL 
 +>GH27_QRW17738.1|ASPOR@510516@000184455_2|XP_001820370.1|1 
 +MQRYISLSVSLSLLSGANALVRPDGVGRLPALGWNTWNAFGCDIDASKVLTAAEETINLGLKDAGYEYINIDDCWSVKSGRDPNTKRIIPDSAKFPDGISGVASKIHDLGLKVGIYSSAGTETCAGYPASLGYEKIDAESFAEWGIDYLKYDNCGVPTNWTDTYTHCVPDNSNGSKFPNGTCPDISNPAPTAYDWSSSNTAQRYNAMRDALLGVNRTILYSLCEWGQADVNTWGNGTGNSWRTTGDITPDWSRIVEIANENSFLMNYADFWGYPDPDMLEVGNGNLTLEENRAHFALWAAMKSPLIIGTALDSINEEHLAILKNKPLLSFHQDPVIGRPAYPYKWGYNPDWTFDPAHPAEYWSGPSSTLGGTLVLMFNSEDSAKHRTAVWSEIPELKDSAEKGSGYRVTEIWTGEDLGCVKDQYDVELQSHDIAALVVGESC 
 +>GH27_QRW17738.1|TRIVA@412133@000002825_2|XP_001315888.1|1 
 +MLISFLQLATSTEYETPTMGWSSWNTYRVHISEELIKKQATAMAEKGLKEKGYKYINIDDGYFGGRNETTGQLLINPERFPNGLEPVVTHIHNLGFKAGIYSDGGRNTCGNYYDADVLGKGVGLYAHDDQDADLFFNTLQFDFIKLDYCGGDPNQNSERLNLDEQTRYTSIRKALNKITRSIRVNVCRWAYPGSWVTKLATSWRISSDIENNFDAIKRLINVNMFYSAYAVEGHYNDMDMLEVGRGMSDDEDKTHFGMWCIMSSPLLIGCDMTTIKDSTLELLKNEELIALNQDPLALQAQLVETQSNTFIFVKDILEYHSTTRAFAVYNPSDSEQTVNINFESLGLSGNIKVRDVYAKSDVGTYPSSQPFSVKVNKHGTRIFTISGETRLEQVRYEAENSWIERGSAITSAQVARVDSDSLCSLGHKVTYIGGNENDNYIEWRDVYSQNGGKYNMKIAFLSGEDRILRVIVNGKTNVLKLNAGSWTAVGTKTIEIELQKGSNVIRMDNPISFAPDIDYFEITPV 
 +>GH27_QRW17738.1|CORMI@983644@000225605_1|XP_006673409.1|1 
 +MGFLAALSSASPYSSILDLASTMKSQLVLASAAGLATSTHVDLPLPPMGFNNWARFTTHINQSIFTDAATSMAANGMLAAGYNRLNLDDAWSTHERAANGSMVVDSVKFPQGLSWLAAFIKDKGFIPGIYTDSGTLSCGQYPAAYGHEAIDLQDFSDWGYEYLKLDGCNVPGEDEAAYRRVYFDVWRELLLTFPKPVVFSNSAPAYFCGADNLTDWYSIMGWAQQMGQLARHSYDIINYDSKGSAWDSLMTNYNQHVRLARYQRPNFFNDPDFLNTDHPNYTLEEKKTHMALWSSFSAPLIVSADIPNLKKEELEILLNKDLIAIDQDPLVQQATLVSSSPDWDVLSKNLANGDRVLTILNKAGKAGDYTVPWARIGIQTDRISPDTALSVKDLWTGKTEQVKISAGGITAKNVGPHGTFVYRISGRMGGSSHPIVLPTGLIFNTFSLKCLSDDKSGKVAWKTCDGSDGQTWTVSDEGRVHSLLRPNECLADVQGKLLSRHSGCRTDAWKYYNSGNLVNGNSNRCLTEGAAGAASVSDCGYATNEQVIGLPVGAKVIEVDYYANK 
 +>GH27_QRW17738.1|BRACO@38358@014529535_1|XP_037033872.1|1 
 +MFSASVIIVCVLVTSQVYALENGLARTPPMGWMTWQRFRCTTDCNIFPNDCISENLIKRTVDALVRDGYRDAGYEYVIIDDCWPEMERSSEGLLVPDKNRFPSGMKALSDYIHARGLKFGIYQDYGTKTCAGYPGIIGYQELDAILFASWGVDYVKLDGCYSEPESMDEGYVSFGQLLNKTGRPMVYSCSWPVYQEEKGIEPNFTLISEHCNLWRNWDDINDSWSSLASIADYFAKNQERIQRFAGPGHWNDPDMLLIGNFGLSLEQSKVQMSLWAILAAPLLMSNDLDTIRPEFKDILLNREILSINQDPLGIQGTRVKVIDNIEIWTRPILPRTDSSHSFAVAYVSLRTDGAPHRIQLNLVDIGLTNLGGYVEMDVFEDTVSPTVKYPETLSSVIVNPTSCVLHKFVAL 
 +>GH27_QRW17738.1|BRACO@38358@014529535_1|XP_037037659.1|0 
 +MIYPRSPPHIVLIILSLLAVAYHINGLDNGLARTPPMGWLSWERFRCNTDCEGDPDNCISENLFRTMADLVVSEGYAALGYEYINVDDCWLEKSRGPQGQLVADRKRFPRGMRSLSDYVHSKGLKFGIYEDYGNYTCAGYPGIIGYGRSDAQQFADWNVDYVKLDGCYSLPLDMDQGYPEFGRHLNSTGRQMIYSCSWPVYQIYAGISPNFSSIIEHCNLWRNYDDIQDSWASLETIIDYYGNNQDAIVPNAGPGHWNDPDMLIIGNFGLSYEQSKTQFALWAIMAAPLLMSVDLRTIRPEFKAILQNQKIIAVDQDPLGIQGRRIYKHKGIEIWSRPITPIYQTYYSYAVAFVNRRTDGTPSDVAVTLRELGLQSPTGYRVEDLYEDVNYGILSPNTKIKVKVNPSGVVILSAHVQPERITRTTYNPLNYYHVK 
 +>GH27_QRW17738.1|BRACO@38358@014529535_1|XP_037037657.1|0 
 +MIMIYPRSPPHIVLIILSLLAVAYHINGLDNGLARTPPMGWLSWERFRCNTDCEGDPDNCISENLFRTMADLVVSEGYAALGYEYINVDDCWLEKSRGPQGQLVADRKRFPRGMRSLSDYVHSKGLKFGIYEDYGNYTCAGYPGIIGYGRSDAQQFADWNVDYVKLDGCYSLPLDMDQGYPEFGRHLNSTGRQMIYSCSWPVYQIYAGISPNFSSIIEHCNLWRNYDDIQDSWASLETIIDYYGNNQDAIVPNAGPGHWNDPDMLIIGNFGLSYEQSKTQFALWAIMAAPLLMSVDLRTIRPEFKAILQNQKIIAVDQDPLGIQGRRIYKHKGIEIWSRPITPIYQTYYSYAVAFVNRRTDGTPSDVAVTLRELGLQSPTGYRVEDLYEDVNYGILSPNTKIKVKVNPSGVVILSAHVQPERITRTTYNPLNYYHVK 
 +>GH27_QRW17738.1|BRACO@38358@014529535_1|XP_037050710.1|0 
 +MWSKILSFVLLLWQQNKCLVDALDNGLALTPPMGWMSWQRFRCIIDCDLYPDECISERLFKTAADVIASEGYKDVGYEYVIIDDCWLESERDNVTKELVPDRKRFPNGMKALADYVHSKGLKFGIYENYGAKTCEGYPGIIDHMELDAKTFAKWDVDYIKVDGCYADYLDYDVGYPEFGRLLNKTGRPMVYSCSWPVYQEIKGLTPDYEALKQHCNLWRNWKDIQDSYESLRNITEYFAVNQSRIQPHAGRGHWNDADMLLIGNYGLSIDQSKTQMAIWAVIASPLIMSNDLKNIRPEFKEILLNKEVIDVSQDELGVQGIRKRFEARIETWMRPIKPIVNGELSYAIAWSSKRIDGAPFTVSANVGSLKLTNANGYRVTDLFNKNRFVMDILPAQNITVRVNPSGVVFYKFTAK 
 +>GH27_QRW17738.1|HYDVU@6087@000004095_1|XP_002159485.2|1 
 +MLYLLIISQIVGLYTLDNGLARTPPMGWLQWERFRCIIDCETYPDQCISENLFKRTADKLVSDGYAKLGYKYVNIDDCWPELQRDLDGNLVADKKRFPNGIKALADYIHNHGLKMGIYTDFGTLTCGGYPASIFHMQKDTQIFSNWGVDMVKLDGCYACESLYADGYKAFGWYMNQTERPMLYSCSWPAYVEKNKFDXLLIGDYSLSESQSKVQFALWSILAAPLFISADLDTMKQWQKDILLNEEIIAVNQDVLGKMGRRVYKDNNQQNWVRYLDNNAAAVAIMSLRTDIPVYMEVTFSSINMKGPFHVRDLFLHEDLGVFNTSFKAIVDPVGVVMVKLTPMA 
 +>GH27_QRW17738.1|NOTCE@1203425@009762535_1|XP_034555657.1|1 
 +MHLAVFLLASTLSAITFALDNGEMRTPPMGWLAWERFRCDIDCKNDPKNCISENLFIDMADRLAEDGWRELGYTYVNIDDCWASMERDENGRLQADPKRFPGGIPRLSRYMHDRGLKLGIYGDMGTHTCGGYPGTPLDKIEVDAQTFADWEVDMLKFDGCYSNASEQEKGYPLMSKALNATGRPIGYSCSWPAYQGGLPPKVNYTQLGEICNLWRNYGDIQDSWGSVLSIADWFFENQDILIPAAGPGRWNDPDMLVVGDFGLSMDQSRSQMALWAIMAAPLFMSNDLRTISSGARNILQNKMIISINQDPMGIQGRRIVKEKSHIEVFWRSLSNGASALVFFSRRTDMPYRYQTSLSKLNYTTGSYKIYDVYTDQTTMLKDTTNFVVSVNPTGVVMWYVSAPAKLHERHFYKSGNLMESVHRGDENTIPRVFL 
 +>GH27_QRW17738.1|HUMAN@9606@000001405_39|NP_000160.1|1 
 +MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTMQMSLKDLL 
 +>GH27_QRW17738.1|HUMAN@9606@000001405_39|NP_000253.1|0 
 +MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ 
 +>GH27_QRW17738.1|HUMAN@9606@000001405_39|NP_001349777.1|0 
 +MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ 
 +>GH27_QRW17738.1|HUMAN@9606@000001405_39|NP_001349779.1|0 
 +MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ 
 +</file> 
 +</hidden>
  
  
 === Task 2: GH28_QRW23661.1 === === Task 2: GH28_QRW23661.1 ===
 +
 +  - Repeat the analysis using GH28_QRW23661.1 and the following taxon set:<WRAP>
 +<file txt GH28_QRW23661.1_taxa.txt>
 +Spodoptera litura
 +Rhizoctonia solani
 +Rhagoletis zephyria
 +Bradysia coprophila (XP_037032572.1)
 +Protomyces lactucae-debilis
 +Pyricularia oryzae 70-15
 +Arcicela rosea (WP_367284634.1)
 +</file></WRAP>
 +<hidden GH28_QRW23661.1.fa>
 +<file>
 +>WP_367284634.1 glycoside hydrolase family 28 protein [Arcicella rosea]
 +MKKRISLLIAISSAMFCNSLVAQKTPTYSWKNLPKIVQPTFAKDTFNVTKFGAKPDGITLNTQAINDAIT
 +ACSKKGGGVVLVPNGMWLTGPIVLKSNVNLHIRKAATLLFTEDKSQYPLVEGSYEGKSAARNQSPISATN
 +QENIAITGQGIIDGSGDVWRAVNKAQLTESEWNAKKASGGVLKANGLTWYPSEQFMKASVENRSMLLKDG
 +VSLQSFADMKDFLRPNLLVITKCKKVLLEGVTFQNSPAWCLHPLMSENLTLRNLTIKNPEYAHNGDGMDI
 +ESCKNFLVDGCTIDVGDDAICIKSGKDEEGRKRGMPTENGIIRNCIVYNGHGGFVVGSEMSGGARNIFVY
 +DCTFAGTDKGLRFKSVRGRGGIVENIYAKNIFMKDIAQEAIFFDMYYFVKFATDSPRDERPVVNEGTPIF
 +RNMKFENIVCKGANKGIFVRGLSEMPIQNIQMSNIVLDTKIGAEFIDASNITLEKVTLISENTKPVISVN
 +NSDGLTFNTIQYKANAELLFAIAGERSKAIQILQTDSSKAQKQIEFTEGATKEAITVSTGK
 +>GH28_QRW23661.1|PYROR@242507@000002495_2|XP_003719232.1|1
 +MKLSSLLAMLGVATTATAFMPADRPRNAQEFRAKHPVARRADSGCRRRFTPRASTHDLDDVSAEFEQAVRDANNGGTVHLPKDQLFVIGKPLDLTFLNDIHVKLEGTIRFTNDTPYWQANAFYHPFQRSLMFWKWGGKDIKIYGEGVLDGNGQRWWNEFSGLEILDPDNPYLRPVLFYAENTTNLHVEGIFMKDSPVWHNFVVTSKDVTYKDVIIEAISNNATSPPKNSDFFNSLNVDGVTVERVWVNIGDDCFSPKSNTSNVHVNTMYCNGTHGQSMGSLGQYEGEVSIVENVLIENVALLNGDNGARLKIWAGESVGSGWIRNVTFRNFYAANLDFVARLDSCYFNIPSETCNRFPSKMSIQDITFENFSGTTSGKNGDAVARLTCSTSPDAVCENVVFKNFNITSPCGGAPVVICDGITGLQHGCVAFDSAEAKAAMDNKCKAPVASIEPPWPVRDWRNSK
 +>GH28_QRW23661.1|RHISO@456999@016906535_1|XP_043183898.1|1
 +MLSAILAVALGAAVALASKTGVKTQTCIVPSHGNVNISDTPAVHATFKKCGKGGHIIFSENTNYTLRELTTMTPCIGCTVQLEGTIQMADNITYWLKNETTNTPNITAETFPHLVYYPFQDTVAYLILKDWSHSTLVSKTGKGLIDGLGQLWWDAAVGQQILLPGTLRRPVLFTLDGANNVTVDNVTMRNPANWFNWVTDSSNVVYKNIRLSALSANKNPPANADGWDTYRTSHFELRDSHIVSGDDCFAFKPNSTYITIENVYCQNSHGVSVGSLAQYPGVLDIVEHVKVKNVTFVGNGDSSSNGARIKIWSGPVGSAIVNDIHYEDLRVENVTNPLVVDSCYFSSAYCATGKPVATITNVTVTNITGTSTGKVVSSIICPEGSTCDIKLKNVNIVPKTGVAPVYRCFSVASEDLGVNCTYPTIVNGAFKWPA
 +>GH28_QRW23661.1|PROLA@2754530@002105105_1|XP_040722516.1|1
 +MLPQHCAIAAAWLQLLSLGYATAQGLSISSSHLLTSNAAVKPNPTEANVAPKVCSIKANMNGISKDLLQAAQACKSNGHIIIEAGDSLIDNVVVMADLKDVTISIQGTLHLKADPVFWAQNAYKHDLVNFQNSSAAILFRDCEGLKFGGAEVFKTGSTIIGYGAPFWSAYLADNTIMRPNLVTLQRCTNCEISNLRFLDTPKWAMYVTDSDHVNIHDMMIQSIGGSVMAMNTDGIDIRNSTNVEFHNNYIDNTDDCVAIKGMCSNIYVHDIICGSKTAGVAIGSLGNIVGVNEFVKDVVIQDVLISGTPRGGIRIKIWPGNRVKAKELLGGGGLADVHNITASRIHTSDNSQALYIDTCYSLGRTNSNCYGYPSLGTITDVTIDGIYGTSPTGSFGHVLCSNPSKCQNIKINNVIMATAVDTASGIGTTAVLNTVGVPPSILSGAPADIGLFDLSLPNGCYLERAAYATDSTPVPYFAPKPRDRPLGYLDGVPKTPADCLQPGSKWWLAQGQPSDFTLSTTSYKPPVYPKVHLSQIPASRVKVSPAFPKNG
 +>GH28_QRW23661.1|RHAZE@28612@001687245_1|XP_017491101.1|1
 +LNPVVVQINDSSHIIVSDLTFINSPWFTVAPYRSEYVTIDHVTVKNPSNAPNTDGIHPEACHHVVISNCFVSTGDDGIVITSETDKNTNAKYSSENITVNHCTVHSGHGGIVIGSAISGDVRDIHAHNLHFEGTLRGVRLKSTRDHGGIVENIYIKDITMKNISDEGITISAFYDVKNFDPHNIPSKTFDVSKTPTFRNIHLTNVTGDSKLGLQIVGLPEKHFDKIELKQVHLVAKKEEIIVNADHVLKENFIYKIDKHLHDN
 +>GH28_QRW23661.1|BRACO@38358@014529535_1|XP_037032572.1|0
 +MKNLITIATFIGSVLTSQLLPLPTQFFSSRLGDSAPLDKKFIVENCDYNGRLLAFSIENCTDTEGICNIVTKREYNVNITFEPSVSTSNLIWRVIFNINGQDQVLVERPIYEHVQPGVTYTLFNTFAFGFENEGLSFPATFQIIDASTERAEICHSAVLDVNSWHMVPEILSRIKAPIFPDRDFDITTYGAVPDGETDNTEAFSRAIVHCHLLGGGRVVVPPGVFLSSAITLLSNVNLHLKEGSTILFTQNTTAYPNVFTRLGGLELINFSPFIYAFGAENIALTGSGVLNGNADCEHWWPWKGRNNNLELLCGIIEGFPTEEADVAALTEMAERNVPVEERIFGEGHFMRPVFVQPYNSKNILIEGVTFLRSPNWILNPVLCENVIVRGVTINSTGPNSDGCNPESSKDVLIENVKFITGDDCIAVKSGRNADGRRINVKSENIVIQNCEMENGHGGFTIGSEISGGAQNIFCQNCSMNSPQLEQGLRFKNNAVRGGLIEDIYIRNIHIPELYTGTSASRGMVLSIDFFYEEGPNGNYPPVVRNVDIRNVTALKSNYALYLRGFPTDQITNVRLYDCHFNGVVRGSVIEHVENLGLFNVTVNGDVIEVPAV
 +>GH28_QRW23661.1|SPOLI@69820@002706865_1|XP_022836218.1|1
 +MFCNSLVAQKTPTYSWKNLPKIVQPTFAKDTFNVTKFGAKPDGITLNTQAINDAITACSKKGGGVVLVPNGMWLTGPIVLKSNVNLHIRKAATLLFTEDKSQYPLVEGSYEGKSAARNQSPISATNQENIAITGQGIIDGSGDVWRAVNKAQLTESEWNAKKASGGVLKANGLTWYPSEQFMKASVENRSMLLKDGVSLQSFADMKDFLRPNLLVITKCKKVLLEGVTFQNSPAWCLHPLMSENLTLRNLTIKNPEYAHNGDGMDIESCKNFLVDGCTIDVGDDAICIKSGKDEEGRKRGMPTENGIIRNCIVYNGHGGFVVGSEMSGGARNIFVYDCTFAGTDKGLRFKSVRGRGGIVENIYAKNIFMKDIAQEAIFFDMYYFVKFATDSPRDERPVVNEGTPIFRNMKFENIVCKGANKGIFVRGLSEMPIQNIQMSNIVLDTKIGAEFIDASNITLEKVTLISENTKPVISVNNSDGLTFNTIQYKANAELLFAIAGERSKAIQILQTDSSKAQKQIEFTEGATKEAITVSTGK
 +</file>
 +</hidden>
 +=== Summary and Discussion ===
 +
 +  * Why are there plant cell wall degrading enzymes in animals?
 +  * Why is GH28 of //Spodoptera litura// identical to a bacterial sequence? What are the consequences given the assumptions stated above?
 +
 +{{ :compgenomics:cellulase_all.extended.fa.gz |}}
  
 ---- ----
  
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